Nurse Practitioner / Physician Assistant (Clinical Research)

Overview & Highlights

• Location: Chandler, AZ
• Schedule: Four 10-hour shifts per week (4/10s), Monday–Thursday
• Employment Type: Full-time, exempt
• Compensation: $130,000–$155,000 per year, depending on experience
• Focus: Phase 1 clinical research, liver disease, gastroenterology, and hepatology
• Reports To: VP of Research
• Benefits: 4 weeks PTO, CME budget and time off, health/dental/vision coverage, 401(k) with 6% company match, paid holidays, sick time, and disability coverage

Location & Logistics

• Work Environment: On-site Phase 1 clinical research and specialty patient care setting
• Schedule: Monday–Thursday, four 10-hour shifts
• Friday: No regularly scheduled shift
• Travel: Interoffice travel may be required; company vehicle or mileage reimbursement options available
• On-Call: Participation in the APP call rotation as applicable

About the Opportunity / A Day in the Life

We are seeking an experienced Nurse Practitioner (NP) or Physician Assistant (PA) to join a Phase 1 clinical research team in Chandler, Arizona. This is a specialized opportunity for an APP who understands clinical research and wants to play a meaningful role in bringing emerging therapies to patients.

You will work directly with both standard-of-care and clinical research patients, conducting evaluations and consultations, reviewing pretreatment requirements, performing safety medical reviews, and managing patients throughout their participation in clinical trials. You will also serve in a Sub-Investigator capacity, requiring a strong understanding of study protocols, patient safety, research documentation, and regulatory expectations.

The role is highly collaborative. You will work alongside physicians, clinical research coordinators, research recruiters, and other research professionals to execute study visits, maintain accurate source documentation, review informed consent documentation, and ensure protocols are followed appropriately.

This is also a role with meaningful patient ownership. You will help manage patients from their initial visit through study completion and closeout while contributing to innovative care for individuals affected by liver and gastrointestinal disease.

Why This Role Stands Out

• Four-day workweek with Monday–Thursday 4/10s
• Direct involvement in Phase 1 clinical trials
• Serve as a Sub-Investigator and play an active role in research execution
• Manage patients throughout the clinical trial lifecycle
• Work with complex GI, hepatology, and liver disease patient populations
• Combine advanced clinical practice with research, patient safety, and emerging therapies

What We’re Looking For

• NP or PA with previous clinical research experience
• Strong understanding of clinical trial protocols and research processes
• Comfortable managing clinically complex patients with minimal assistance
• Strong clinical judgment and independent decision-making ability
• Detail-oriented approach to research documentation and protocol compliance
• Effective leader and collaborator who can work across clinical and research teams

Job Duties & Responsibilities

• Perform patient evaluations, consultations, and pretreatment reviews for standard-of-care and clinical research patients.
• Serve in a Sub-Investigator capacity and support the clinical execution of Phase 1 research protocols.
• Oversee appropriate aspects of clinical trial patient care and conduct medical and safety reviews.
• Diagnose conditions and make appropriate treatment decisions within established scope of practice.
• Educate patients regarding therapeutic options available through applicable liver clinical trials.
• Counsel patients and families and coordinate appropriate direct-care interventions with physicians.
• Serve as a primary clinical point of contact and assume responsibility for managing assigned patients.
• Collaborate with clinical research coordinators, recruiters, physicians, and other research personnel to complete study visits.
• Review study documentation, clinical charting, source documentation, and informed consent records for completeness and accuracy.
• Maintain a thorough understanding of assigned protocols and communicate study requirements to research team members.
• Perform applicable in-clinic procedures, including FibroScan, when appropriately trained and qualified.
• Support assigned studies and patients from initial evaluation through study completion and closeout.

Required Qualifications

• Graduate of an accredited Nurse Practitioner or Physician Assistant program
• Current and appropriate NP or PA certification
• Active or eligible license to practice in Arizona
• Nurse Practitioner candidates must maintain applicable RN and NP licensure and certification
• Physician Assistant candidates must maintain applicable NCCPA certification
• Previous clinical research experience with a strong understanding of research processes and protocols
• At least 1 year of experience practicing as an NP or PA in a clinic or hospital setting
• Ability to diagnose and manage clinically complex patients with minimal assistance
• Strong verbal, written, and interpersonal communication skills
• Ability to complete GCP and IATA training upon hire
• Ability to maintain certifications required by the applicable department or division
• Valid documentation and authorization to work in the United States

Preferred Background

• Previous outpatient gastroenterology and/or hepatology experience
• Previous Sub-Investigator experience
• Phase 1 clinical trial experience
• Experience caring for patients with liver disease
• Experience performing FibroScan procedures
• Bilingual English/Spanish skills
• Leadership or mentoring experience within a clinical research environment
• Commitment to continued professional development and additional certifications

Knowledge & Skills

• Strong understanding of clinical research processes, protocols, and patient safety requirements
• Ability to provide patient care with minimal supervision
• Ability to identify and appropriately respond to patient concerns
• Strong awareness of quality-of-care standards and metrics
• Ability to make appropriate patient referrals
• Strong systems and process problem-solving skills
• Resourceful approach to identifying solutions and utilizing available resources
• Ability to mentor research team members on standard operating procedures and best practices
• Proficiency with Microsoft Outlook, Word, Excel, PowerPoint, and OneDrive
• Experience with or ability to effectively use electronic medical record systems, including eCW

This Role Is Likely a Fit If You…

• Have clinical research experience and understand the responsibilities of a Sub-Investigator.
• Want direct involvement in Phase 1 clinical trials and emerging therapies.
• Enjoy combining advanced clinical practice with research responsibilities.
• Are comfortable managing complex patients with a high degree of autonomy.
• Thrive in a multidisciplinary environment with physicians, coordinators, and other research professionals.
• Value a four-day Monday–Thursday workweek.

This Role May Not Be a Fit If You…

• Do not have previous clinical research experience.
• Prefer a traditional clinical position without research or protocol responsibilities.
• Are uncomfortable with detailed source documentation and regulatory requirements.
• Prefer a role with minimal responsibility for complex patient management.
• Are not interested in GI, hepatology, liver disease, or clinical research.
• Prefer a fully remote or hybrid position.

Benefits & Perks

• Medical, dental, and vision insurance
• HSA plan options with employer contribution
• 4 weeks of PTO
• 5 days of sick time
• 7 company holidays plus 2 half-days
• Continuing Medical Education (CME) budget
• Necessary CME time off
• 401(k) with 6% company match
• Short- and long-term disability coverage
• Shared company vehicles for required business travel

Why Join Us

This position offers an uncommon combination of advanced clinical practice, Phase 1 research, specialty medicine, and patient ownership. You will have direct involvement in clinical trials, collaborate with an experienced multidisciplinary research team, and help ensure patient safety while supporting the evaluation of emerging therapies.

The Monday–Thursday 4/10 schedule also provides a consistent four-day workweek while allowing you to build specialized expertise in clinical research, gastroenterology, hepatology, and liver disease.

If you are an experienced NP or PA with clinical research experience who wants a more specialized and impactful role in clinical trials, we encourage you to apply.

Requirements

• Graduate of an accredited Nurse Practitioner or Physician Assistant program
• Current and appropriate NP or PA certification
• Active or eligible license to practice in Arizona
• Nurse Practitioner candidates must maintain applicable RN and NP licensure and certification
• Physician Assistant candidates must maintain applicable NCCPA certification
• Previous clinical research experience with a strong understanding of research processes and protocols
• At least 1 year of experience practicing as an NP or PA in a clinic or hospital setting
• Bilingual English/Spanish skills preferred